Vangelis Pavlidis put Greece ahead early in the second-half, before Jude Bellingham scored a late equaliser for Engald. However, the 25-year-old striker struck again in the stoppage time to hand England interim boss Lee Carlsley the first defeat of his reign.
Messi, who missed Argentina's last round of fixtures in September due to injury, set up Nicolas Otamendi to open the scoring in the 13th minute. However, Venezuela leveled the score through Salomon Rondo's 65th-minute header.
Both sides are heading into the match on the back of 2-1 wins last time month, with Bolivia getting the better of Chile on the road, while Colombia defeated leaders Argentina at home.
Saudi Arabia secured a come-from-behind 2-1 win against China last time out, while Japan thrashed Bahrain 5-0 in their second Group C fixture last month.
Bahrain are sitting at the third spot in Group B, having collected three points from two games, just one point clear of Indonesia, who are at the fourth position.
Both sides have won their first two games and are sitting at the top of Group A, with six points to their name. The visitors are trailing on goals scored.
Both sides are heading into the match on the back of 3-1 wins last month, with Jordan getting the better of Palestine, while South Korea defeated Oman.
Australia endured a miserable September camp and are languishing at the fifth spot in Group C, having collected only one point from two games, with only China behind them, yet to open their account.
Atletico Madrid were held to a 1-1 La Liga draw away to Sociedad at Anoeta on Sunday (local time). Julian Alvarez's early opener was canceled out by Luka Sucic's late screamer.
Although the defender made a cameo appearance as a substitute in Real Madrid's recent 2-0 La Liga-win against Villarreal, further medical examinations have confirmed that Militao will not be able to take part in the crucial qualifiers.